Skip to main content
. 2013 May 21;8(5):e63402. doi: 10.1371/journal.pone.0063402

Figure 6. Reducing heme availability suppresses the intensified rate of oxygen consumption in lung cancer cells.

Figure 6

The normal HBEC30KT lung epithelial (HBEC) and NSCLC HCC4017 (HCC) cells were cultured and treated in normal medium (None), in medium with heme depleted (HD), in medium with heme depleted and succinyl acetone (HD+SA), and in medium with CCCP. Cells were collected and oxygen consumption rates were detected and plotted here. The values plotted were averages from at least three experiments. For statistical analysis, the levels in cancer cells were compared to the levels in normal cells, by using Welch 2-sample t-test. *, p value <0.05; **, p value <0.005.