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. 2013 May 21;104(10):2282–2294. doi: 10.1016/j.bpj.2013.03.057

Figure 3.

Figure 3

Relationship between the time of pheromone addition and Whi5P activation. At the Start point where the maximum slope is achieved in this response curve, there exists one critical addition time that indentifies the critical ratio of Whi5 required for a successful transition of two distinct cell fates. In WT cells, Start is defined by the export of approximately half of the nuclear Whi5.