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Only PMLIV confers resistance to EMCV, rabies virus, and VZV.
| Virus | Higher viral production | Inhibition of viral production | Mechanism | Reference | ||||
|---|---|---|---|---|---|---|---|---|
| RNA viruses | ||||||||
| EMCV | Absence of PML (MEFs PML−/−) | PMLIV | Sequestration of 3D pol in PML NBs | El Mchichi et al. (2010); Maroui et al. (2011) | ||||
| Rabies virus | PMLIV | ND | Blondel et al. (2002, 2010) DNA virus | |||||
| VZV | Depletion of PML (Human cells) | PMLIV | Sequestration of ORF23 in PML NBs | Kyratsous and Silverstein (2009); Reichelt et al. (2011) |
ND, not determined.
