Table IV. Comparison of Neurotoxicity in Study Group to Reference Group.
Group | Study | Reference |
---|---|---|
Treatment Dates | 4/2004-10/2007 | 8/2001-3/2004 |
Treatment Protocol | HLH-2004 or HLH-94 with early introduction of cyclosporine | HLH-94 |
Number of Patients | 17 | 15 |
Male/Female | 5/12 | 9/6 |
Age (yrs) Range Median |
0.1-16 4.9 |
0.2-12 1.6 |
CNS Status at Diagnosis (CNS Dz +/-) |
4/13 | 3/12 |
Survival (Alive/Deceased) |
7/10 | 8/7 |
Neurotoxicity (Present/Absent) |
5/12 | 1/14 |