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Targeted therapy in neuroblastoma: Current approaches to targeted therapy for neuroblastoma involve several modalities including 1. small molecular inhibitors of activated signaling pathways (ALK, IGF1R, MEK, PLK1, AURKA, PI3K and mTOR inhibitors) 2. radiopharmaceuticals targeting the NET receptor (131I-MIBG, 211At-MABG) and 3. immunotherapy (anti-GD2 antibodies).
