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. 2012 Jun 28;27(9):1182–1185. doi: 10.1002/mds.25102

Table 1.

Demographic data, clinical data, TCS results of study patients, and diagnostic accuracy of midbrain hyperechogenicity for the differential diagnosis of PD versus SWEDD

Demographic and Clinical Data PD Patients SWEDD Patients PD Versus SWEDD
Patients, n 19 14
Female/male, n 7:12 7:7 0.497
Age, years (mean ± SD) 63.3. ± 7.5 68.2 ± 10.8 0.130
Age at onset, years (mean ± SD) 55.4 ± 11.8 56.3 ± 11.8 0.830
Disease duration, years (mean ± SD) 7.5 ± 7.2 14.9 ± 11.3 0.030*
DAT-SPECT after disease onset, years (mean ± SD) 7.2 ± 9.3 7.5 ± 7.9 0.900
Sufficient bone window, n (%) 17 (89.5) 11 (78.5) 0.630
Midbrain hyperechogenicity, n (%) 14 (82.5) 1 (9.1) <0.001*
UPDRS motor score, mean ± SD 18 ± 10 10.8 ± 3.7 0.020*
Sensitivity, % 82.4 (58.2–94.6)
Specificity, % 90.9 (60.1–99.9)
PPV, % 93.3 (68.2–99.9)
NPV, % 76.9 (49.1–92.5)
Overall accuracy, % 85.7 (67.9–94.9)
Likelihood ratio 9.06
TP, n 14
FP, n 1
FN, n 3
TN, n 10

Data in parentheses are the confidence intervals.

*

Significance level: P < 0.05.

Abbreviations: TP, true positive; FP, false positive; FN, false negative; TN, true negative.