Table 2.
Pathologic Characteristics according to mSEPT9 Status in 83 CRC Patients and 138 GC Patients with Pathologic Examination of Radical Surgery Specimens.
| mSEPT9 | P Value | |||
| Positive | Negative | Total | ||
| CRC | ||||
| Histologic grade | NS | |||
| WD | 3 (42.9%) | 4 (57.1%) | 7 | |
| MD | 24 (34.8%) | 45 (65.2%) | 69 | |
| PD | 1 (33.3%) | 2 (66.7%) | 3 | |
| Mucinous | 1 (25.0%) | 3 (75.0%) | 4 | |
| Tumor size | 5.75 ± 2.73 | 3.99 ± 1.92 | 4.59 ± 2.37 | .004 |
| Depth of invasion | NS | |||
| pTis/T1 | 4 (28.6%) | 10 (71.4%) | 14 | |
| pT2 | 4 (25.0%) | 12 (75.0%) | 16 | |
| pT3 | 14 (35.9%) | 25 (64.1%) | 39 | |
| pT4 | 7 (50.0%) | 7 (50.0%) | 14 | |
| LN metastasis | NS | |||
| pN0 | 19 (35.8%) | 34 (64.2%) | 53 | |
| pN1 | 6 (28.6%) | 15 (71.4%) | 21 | |
| pN2 | 4 (44.4%) | 5 (55.6%) | 9 | |
| Lymphatic invasion | NS | |||
| Absent | 20 (31.7%) | 43 (68.3%) | 63 | |
| Present | 9 (45.0%) | 11 (55.0%) | 20 | |
| Venous invasion | .044 | |||
| Absent | 22 (30.6%) | 50 (69.4%) | 72 | |
| Present | 7 (63.6%) | 4 (36.4%) | 11 | |
| Perineural invasion | NS | |||
| Absent | 19 (30.2%) | 44 (69.8%) | 63 | |
| Present | 10 (50.0%) | 10 (50.0%) | 20 | |
| Tumor deposits | NS | |||
| Absent | 22 (34.4%) | 42 (65.6%) | 64 | |
| Present | 7 (36.8%) | 12 (63.2%) | 19 | |
| Preexisting adenoma | NS | |||
| Absent | 26 (40.0%) | 39 (60.0%) | 65 | |
| Present | 3 (16.7%) | 15 (83.3%) | 18 | |
| Other findings | .004 | |||
| Absent | 19 (30.2%) | 44 (69.8%) | 63 | |
| Mucin production | 1 (12.5%) | 7 (87.5%) | 8 | |
| Peritumoral abscess | 9 (75.0%) | 3 (25.0%) | 12 | |
| Total | 29 | 54 | 83 | |
| GC | ||||
| Lauren classification | .009 | |||
| Intestinal | 12 (23.5%) | 39 (76.5%) | 51 | |
| Diffuse | 6 (7.3%) | 76 (92.7%) | 82 | |
| Mixed | 2 (40.0%) | 3 (60.0%) | 5 | |
| Tumor size | 5.54 ± 3.63 | 4.37 ± 2.88 | 4.54 ± 3.02 | NS |
| Depth of invasion | NS | |||
| pT1 | 6 (12.2%) | 43 (87.7%) | 49 | |
| pT2 | 1 (4.5%) | 21 (95.5%) | 22 | |
| pT3 | 7 (20.0%) | 28 (80.0%) | 35 | |
| pT4 | 6 (18.8%) | 26 (81.3%) | 32 | |
| LN metastasis | NS | |||
| pN0 | 9 (14.1%) | 55 (85.9%) | 64 | |
| pN1 | 3 (14.3%) | 18 (85.7%) | 21 | |
| pN2 | 1 (4.5%) | 21 (95.5%) | 22 | |
| pN3 | 7 (22.6%) | 24 (77.4%) | 31 | |
| Lymphatic invasion | NS | |||
| Absent | 10 (14.9%) | 57 (85.1%) | 67 | |
| Present | 10 (14.1%) | 61 (85.9%) | 71 | |
| Venous invasion | NS | |||
| Absent | 16 (14.0%) | 98 (86.0%) | 114 | |
| Present | 4 (16.7%) | 20 (83.3%) | 24 | |
| Perineural invasion | NS | |||
| Absent | 13 (17.1%) | 63 (82.9%) | 76 | |
| Present | 7 (11.3%) | 55 (88.7%) | 62 | |
| Tumor border | .001 | |||
| Expanding | 11 (33.3%) | 22 (66.7%) | 33 | |
| Infiltrative | 9 (8.6%) | 96 (91.4%) | 105 | |
| Preexisting adenoma | NS | |||
| Absent | 18 (13.8%) | 112 (86.2%) | 130 | |
| Present | 2 (25.0%) | 6 (75.0%) | 8 | |
| Total | 20 | 118 | 138 | |
WD indicates well differentiated; MD, moderately differentiated; PD, poorly differentiated; NS, not significant.