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Structure and characterization of PTPµ targeted and control contrast agents. (A) The structure of the targeted contrast agent SBK2-Tris-(Gd-DOTA)3 is shown. (B) MALDI-TOF mass spectra characterization of the nontargeted control [scrambled Tris-(Gd-DOTA)3] and targeted contrast agent [SBK2-Tris-(Gd-DOTA)3]. (C) Plots of relaxivity versus the concentration of gadolinium (mM) of the contrast agents scrambled Tris-(Gd-DOTA)3 and SBK2-Tris-(Gd-DOTA)3.
