Table 1.

Patient and Disease Characteristics at Baseline.

Characteristics	Overall (N = 118)		Oxaliplatin-Based (N = 83)		Irinotecan-Based (N = 35)
	No. of Patients	%	No. of Patients	%	No. of Patients	%
Sex
Male	67	57	45	54	22	63
Female	51	43	38	46	13	37
Age, years
Median	61		60		64
Range	15–86		15–86		25–81
>50	96	81	66	80	30	86
≤50	22	19	17	20	5	14
KRAS
Wild type	72	61	52	63	20	57
Mutant	46	39	31	37	15	43
Tumor site
Proximal*	34	29	27	33	7	20
Distal†	84	71	56	67	28	80
No. of metastatic sites
1	67	57	50	60	17	49
2	41	35	27	33	14	40
≥3	10	8	6	7	4	11
Initial stage
I–III	38	32	19	23	19	54
IV	80	68	64	77	16	46

^*Proximal indicates cecum, ascending colon, hepatic flexure, and transverse colon.

^†Distal indicates splenic flexure, descending colon, sigmoid colon, and rectum.