Representative experiment showing the growth of EMT6 tumors treated on day 13 with large single doses of Laromustine and radiation, alone or in combination. Points are means ± SEM for 5–6 tumors within a single experiment; a replicate experiment gave similar findings. The growth delays, calculated as the excess time needed for treated tumors to reach 4 times the treatment volume, were 6.2 ± 0.8, 3.4 ± 1.8, 6.8 ± 0.8, 7.6 ± 0.4 and 7.9 ± 0.8 days for 10 Gy, 10 and 20 mg/kg Laromustine, and 10 Gy + 10 and 20 mg/kg Laromustine, respectively.