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. Author manuscript; available in PMC: 2013 May 22.
Published in final edited form as: Behav Brain Res. 2011 Jun 21;224(2):350–357. doi: 10.1016/j.bbr.2011.06.016

Figure 7. 5-HT1B mRNA Regulation After Chronic Stress.

Figure 7

A) Ten consecutive days of social defeat stress significantly increased 5-HT1B mRNA signal in the NAcSh at 1.0 mm anterior to bregma. There were no differences in mRNA expression in the NAc core (B) or in the dorsomedial striatum (C). D) At −0.26 mm posterior to bregma, chronic stress increased 5-HT1B mRNA expression in the dorsolateral striatum. E) A representative picture of 5-HT1B mRNA hybridization signal from a chronially defeated animal is shown beside a panel adapted from the Paxinos and Watson rat brain atlas [64] (1.0 rostral to bregma is depicted). Striatal regions that were quantitated have been circled and include dorsolateral striatum, dorsomedial striatum, NAc core, and NAcSh. *=p<0.05.