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. Author manuscript; available in PMC: 2013 May 22.
Published in final edited form as: Int J Radiat Biol. 2012 Sep 3;89(1):16–25. doi: 10.3109/09553002.2012.717733

Figure 6.

Figure 6

Effect of PHY906 on the tumor growth delay induced by fractionated irradiation. Tumors were stratified by volume on day 10 into groups (6 mice/group) which were randomly assigned to receive no treatment, radiation alone, or radiation + PHY906. PHY906 was given twice daily by oral gavage at a dose of 500 mg/kg/treatment. Tumors were irradiated locally with 4 daily fractions of 2.5 Gy per fraction, given 30 min after the morning PHY906 treatment. Points are means ± SEM. This graph shows tumor growth curves from a representative experiment. Analyses of the growth delays from this experiment are shown in row 3 of the Table. Similar results were found in a replicate experiment using this same regimen, and also in two experiments examining tumor growth after a single dose of 10 Gy. Growth delay data from all 4 tumor growth experiments are summarized on the Table.