Table 2. Comparison of the CARD8 CARD structure (PDB entry 4ikm) with other CARD structures using the PDBeFold server (http://www.ebi.ac.uk/msd-srv/ssm/cgi-bin/ssmserver).

CARD (PDB code)	Z score	R.m.s.d. (Å)	Aligned residues	Identity (%)
NLRP1 (3kat)	8.9	1.2	78	32
NOD1 (2nz7)	8.6	1.2	75	19
Apaf-1 (1cy5)	8.3	1.4	77	18
ICEBERG (1dgn)	7.5	1.5	79	24
Procaspase-9 (3ygs)	7.0	2.0	75	15
RIG-I (2lwe)	5.9	2.0	71	17