Table 2.
Population Results | |||
---|---|---|---|
Mean (SD) | Median (range) | Interquartile range | |
Clearance (L/hr) | 11.8 (4.6) | 11.6 (2.2-24.1) | 8.5-14.4 |
Clearance (L/hr/70kg) | 0.17 (0.07) | 0.17 (0.03-0.34) | 0.12-0.21 |
Clearance (L/hr/pop median wt) | 0.54 (0.2) | 0.53 (0.10-1.11) | 0.39-0.66 |
Clearance (L/hr/1.85m2) | 6.4 (2.5) | 6.27 (1.2-13.0) | 4.63-7.78 |
Therapeutic Dose (mg/m2/dose) | 2.0 (0.7) | 1.9 (0.77-3.9) | 1.52-2.41 |
Therapeutic Dose (mg/kg/dose) | 0.08 (0.04) | 0.07 (0.02-0.19) | 0.06-0.09 |
Therapeutic dose ((mg/kg)ˆ0.75) | 0.14 (0.05) | 0.13 (0.06-0.29) | 0.11-0.16 |