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. Author manuscript; available in PMC: 2014 Jun 1.
Published in final edited form as: Ther Drug Monit. 2013 Jun;35(3):332–337. doi: 10.1097/FTD.0b013e318286dd3f

Table 2.

Population Results
Mean (SD) Median (range) Interquartile range
Clearance (L/hr) 11.8 (4.6) 11.6 (2.2-24.1) 8.5-14.4
Clearance (L/hr/70kg) 0.17 (0.07) 0.17 (0.03-0.34) 0.12-0.21
Clearance (L/hr/pop median wt) 0.54 (0.2) 0.53 (0.10-1.11) 0.39-0.66
Clearance (L/hr/1.85m2) 6.4 (2.5) 6.27 (1.2-13.0) 4.63-7.78
Therapeutic Dose (mg/m2/dose) 2.0 (0.7) 1.9 (0.77-3.9) 1.52-2.41
Therapeutic Dose (mg/kg/dose) 0.08 (0.04) 0.07 (0.02-0.19) 0.06-0.09
Therapeutic dose ((mg/kg)ˆ0.75) 0.14 (0.05) 0.13 (0.06-0.29) 0.11-0.16
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