Fig. 2.
Amino acid sequences within S6 segments D1–S6, D2–S6, D3–S6, and D4–S6 of the rat skeletal muscle Na+ channel Nav1.4. Residues in gray are critical for LA binding. The putative gating hinge at position 12 containing a glycine/serine residue [30, 48] is underlined. This figure is modified from Nau and Wang [25].