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. 2012 Oct;192(2):651–669. doi: 10.1534/genetics.112.139519

Table 3 . Posterior joint probabilities of true genotypes gi and IBD states si at a single locus ℓ of an individual i.

Observed genotype True genotype IBD state Joint probability Posterior probability
wi gi si ℙ(gi, si, wi|Ψ) ℙ(gi, si|wi, Ψ)
AkAh AkAh 1 0 0
0 2(1 − ρ)φkφh(1 − γi)2 1
Others 1 0 0
0 0 0
AkAk AkAh 1 0 0
0 2(1 − ρ)φkφhγi(1 − γi) 2(1ρ)φhγiρ(1+γi)+(1ρ)(2γiφkγi+φk)
AkAk 1 ρφk(1γi2) ρ(1+γi)ρ(1+γi)+(1ρ)(2γiφkγi+φk)
0 (1ρ)φk2(1γi2) (1ρ)φk(1+γi)ρ(1+γi)+(1ρ)(2γiφkγi+φk)
XX AkAh 1 0 0
0 2(1ρ)φkφhγi2 2(1 − ρ)φkφh
AkAk 1 ρφkγi2 ρφk
0 (1ρ)φk2γi2 (1ρ)φk2

The calculation of ℙ(gi, si | wi, Ψ) is based on Equation 8. hk.

HHS Vulnerability Disclosure