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. Author manuscript; available in PMC: 2013 Dec 1.
Published in final edited form as: Biol Trace Elem Res. 2012 Sep 19;150(0):467–476. doi: 10.1007/s12011-012-9503-9

Table 1.

Effects of calcium alone and calcium plus gadolinium at different concentrations on proliferation of HCT-116 cells and SW480 cells

Conditions Number of cells ×10−4

HCT-116 SW480
1.5 mM calcium 13.2±0.1 14.4±0.2
3.0 mM calcium   9.9±0.1   9.8±0.2
+1 µM Gd3+   9.3±0.2   9.6±0.1
+5 µM Gd3+   7.5±0.3*   8.2±0.1*
+10 µM Gd3+   4.0±0.1*   7.9±0.3*
+25 µM Gd3+   1.3±0.1*   3.9±0.1*
+50 µM Gd3+   0.8±0.1*   1.9±0.2*
4.5 mM calcium   6.1±0.2   6.4±0.1
+1 µM Gd3+   6.0±0.1   6.0±0.3
+5 µM Gd3+   5.4±0.4*   5.9±0.2
+10 µM Gd3+   4.8±0.1*   5.9±0.1
+25 µM Gd3+   2.0±0.2*   4.0±0.2*
+50 µM Gd3+   1.7±0.1*   2.6±0.4*

Values shown are means and standard deviations based on a single experiment with three samples per data point for each condition. Statistical significance of the data was assessed by ANOVA, followed by paired-group comparisons. The experiment was repeated three times with similar results

*

p<0.05 (statistically significant decrease relative to controls)