Table 3.
Baseline | Ratio short term/baseline | Ratio long term/baseline | |
---|---|---|---|
AUC (ng*h/mL) | 67.4 (73.4) | 1.6 (0.9) | 0.8 (0.5) |
C max (ng/mL) | 24.5 (37.2) | 1.7 (1.4) | 0.9 (0.6) |
T max (h) | 1.4 (1.2) | 2.2 (1.8) | 2.9 (3.1) |
Data are given as mean ± standard deviation. Ratios are calculated with short- or long-term values (numerators) and with values at baseline (before surgery) as denominators
AUC area under the plasma concentration versus the time curve, C max maximum plasma concentration, T max time to reach C max