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. 2013 Apr 19;29(11):1448–1454. doi: 10.1093/bioinformatics/btt170

Fig. 2.

Fig. 2.

Initial reconstruction based on GWDT and comparison results with or without GWDT. (A) The main GWDT-based skeleton (the major mid-curves) of the tracing implies a good tracing. Sphere: the seed location. Also shown is the out-of-center problem, where the left figure is without GWDT preprocessing and the right figure indicates the main structure goes to the neuron center with GWDT preprocessing. (B) top: parallel-path problem without GWDT preprocessing; bottom: parallel paths disappear after GWDT preprocessing