Table 2.

Dose escalation enrollment (N = 21)

Dose Level/Days per Week	n Patients	DLT Observed
1 = 0.15 mg/kg/dose 1× per wk	3	0
2 = 0.15 mg/kg/dose 2× per wk	3	0
3 = 0.15 mg/kg/dose 3× per week	3	0
4 = 0.15 mg/kg/dose 4× per week	6	1 grade 4 neutropenia
5 = 0.15 mg/kg/dose 5× per week	6	0