Table 1. Spearman correlation coefficient between CpG sites methylation of leptin gene promoter (n = 47) and adiponectin gene loci C1 and E2 (n = 97) in maternal and fetal sides of placenta.
| CpG sites | rs | p value |
|---|---|---|
|
LEPTIN |
|
|
|
1–2–3 |
0.31 |
0.04 |
|
4–5–6 |
0.12 |
0.43 |
|
7 |
0.30 |
0.04 |
|
8 |
0.22 |
0.13 |
|
9–10 |
0.40 |
< 0.01 |
|
11 |
0.01 |
0.96 |
|
12 |
0.19 |
0.19 |
|
13–14 |
0.32 |
0.03 |
|
15 |
0.54 |
< 0.01 |
|
16–17 |
0.37 |
0.01 |
|
19–20–21 |
0.44 |
< 0.01 |
|
22 |
0.23 |
0.12 |
|
23–24–25 |
0.34 |
0.02 |
|
26–27–28 |
0.31 |
0.04 |
|
29–30–31 |
0.25 |
0.09 |
|
1 to 31 (mean) |
0.20 |
0.17 |
|
ADIPOQ-C1 |
|
|
|
1 |
0.30 |
< 0.01 |
|
2 |
0.13 |
0.22 |
|
3 |
0.24 |
0.02 |
|
4 |
0.27 |
0.01 |
|
1 to 4 (mean) |
0.18 |
0.07 |
|
ADIPOQ-E2 |
|
|
|
1 |
0.02 |
0.84 |
|
2 |
0.25 |
0.02 |
|
3 |
0.06 |
0.56 |
|
4 |
0.10 |
0.34 |
| 1 to 4 (mean) | 0.14 | 0.17 |