Table 1. Patients’ characteristics and ΔΔCt cluster.
Characteristics | Total (n = 89) |
#NKp30High (n = 20) |
#NKp30Int (n = 42) |
#NKp30Low (n = 23) |
Statistics | |||
---|---|---|---|---|---|---|---|---|
Sex* |
p1 |
|||||||
Men |
67 (75%) |
15 (75%) |
31 (74%) |
17 (74%) |
1 |
|||
Women |
22 (25%) |
5 (25%) |
11 (26%) |
6 (26%) |
||||
Mode of transmission* |
||||||||
Men from Men |
31 (69%) |
13 (65%) |
27 (64%) |
17 (74%) |
0. 69 |
|||
Men from Women |
6 (7%) |
2 (10%) |
4 (10%) |
0 (0%) |
||||
Women from Men |
22 (25%) |
5 (25%) |
11 (26%) |
6 (26%) |
||||
Time (in months) from infection to ** |
p2 |
|||||||
Inclusion |
6.2 [1.3–43.5] |
5.4 [2.7–41.2] |
8.9 [1.3–43.5] |
6.1 [2.1–10.1] |
0.08 |
|||
NKp30 study |
38.3 [3.6–44.4] |
40.0 [8.5–44.0] |
28.0 [3.6–44.4] |
41.8 [17.2–44.4] |
0.008 |
|||
Biological markers** |
p2 |
p3 |
||||||
At inclusion |
||||||||
CD4+ cells |
556 [72–1330] |
458.5 [268–1260] |
542 [72–1193] |
616 [224–1330] |
0.05 |
0.09a |
||
Log(HIV-1 RNA) |
4.1 [2.4–5.6] |
4.3 [3.5–5.6] |
4.1 [3.1–5.3] |
3.9 [2.4–5.5] |
0.18 |
0.18a |
||
Log(HIV-1 DNA) |
2.8 [1.7–4.0] |
2.8 [1.8–3.6] |
2.7 [1.7–3.7] |
2.9 [1.7–4.0] |
0.57 |
0.60a |
||
At NKp30 status assessment |
||||||||
CD4+ cells |
478 [19–1193] |
479 [244–797] |
490 [72–1193] |
456 [19–917] |
0.60 |
0.62b |
||
Log(HIV-1 RNA) |
4.0 [2.4–5.6] |
3.7 [3.0–5.5] |
4.0 [3.0–5.1] |
4.0 [2.7–5.6] |
0.99 |
0.99b |
||
Log(HIV-1 DNA) | 2.9 [1.6–5.2] | 3.0 [2.0–5.2] | 2.9 [1.9–3.7] | 3.0 [1.6–4.0] | 0.75 | 0.45b |
# ΔΔCt cluster groups; *number (%); **median [min-max]; 1Fisher’s exact test; 2Kruskal-Wallis rank sum test; 3Linear regression adjusted for: amean time from contamination to inclusion in the study, bmean time from contamination to NKp30 status assessment.