Table 2. Patients’ characteristics and ratio cluster.
Characteristics |
#Low C (n = 40) |
#Low B (n = 15) |
#High C (n = 28) |
Statistics | |||
---|---|---|---|---|---|---|---|
Sex* |
|
|
|
|
p1 |
|
|
Men |
30 (75%) |
11 (73%) |
22 (79%) |
|
0.89 |
|
|
Women |
10 (25%) |
4 (27%) |
6 (21%) |
|
|
|
|
Mode of transmission* |
|||||||
Men from Men |
27 (68%) |
11 (73%) |
19 (68%) |
|
0.87 |
|
|
Men from Women |
3 (8%) |
0 (0%) |
3 (11%) |
|
|
|
|
Women from Men |
10 (25%) |
4 (27%) |
6 (21%) |
|
|
|
|
Time (in months) from infection to** |
|
p2 |
|
||||
Inclusion |
6.0 [1.3–43.5] |
6.8 [1.8–35.5] |
6.6 [1.3–36.5] |
|
0.72 |
|
|
NKp30 study |
38.7 [4.7–44.3] |
35.5 [10–44] |
39.2 [3.6–44.4] |
|
0.75 |
|
|
Biological markers** |
|
|
|
p2 |
|
p3 |
|
At inclusion |
|
|
|
|
|
|
|
CD4+ cells |
485.5 [202–987] |
874 [415–1330] |
542 [72–1193] |
< 0.01 |
|
< 0.01a |
|
Log(HIV-1 RNA) |
4.2 [3.4–5.6] |
3.5 [2.4–4.9] |
4.1 [2.9–5.5] |
0.06 |
|
0.02a |
|
Log(HIV-1 DNA) |
3 [1.8–4] |
2.6 [1.7–3.2] |
2.7 [1.7–3.5] |
0.17 |
|
0.16a |
|
At NKp30 status assessment |
|||||||
CD4+ cells |
457.5 [19–987] |
578 [305–940] |
488 [72–1193] |
0.16 |
|
0.09b |
|
Log(HIV-1 RNA) |
4 [3–5.6] |
3.7 [3.1–5] |
4 [2.7–5.4] |
0.62 |
|
0.33b |
|
Log(HIV-1 DNA) | 3.2 [1.6–5.2] | 2.6 [1.7–3.5] | 2.9 [1.9–3.7] | 0.14 | 0.10b |
# Ratio cluster groups; *number (%); ** median [min-max]; 1Fisher’s exact test; 2Kruskal-Wallis rank sum test; 3Linear regression adjusted for: amean time from contamination to inclusion in the study, bmean time from contamination to NKp30 status assessment.