TABLE 4.
Parameter Estimates (with 95% CI) for the Generalized Multiplicative (Eq. 2) and Generalized Additive (Eq. 3) Excess Relative Risk (ERR) Models for Plutonium and External Dose by Smoking Statusa
Generalized multiplicative modelb
|
Generalized additive modelc
|
|||
---|---|---|---|---|
Smokers | Nonsmokers | Smokers | Nonsmokers | |
Plutonium ERR per Gy at age 60 | 6.9 (4.6 to 10) | 29 (9.8 to 83) | 92 (45 to 213) | 25 (9.2 to 71) |
P for smoking status difference in plutonium ERR per Gy | 0.011 | <0.001 | ||
Ratio (Nonsmoker:smoker) | 4.1 (1.4 to 12) | 0.27 (0.13 to 0.54) | ||
Gender ratio (F:M) | 0.98 (0.3 to 3.4) | 1.2 (0.3 to 4.4) | ||
External dose ERR per Gy | 0.11 (−0.06 to 0.36) | 0d |
Restricted to workers with data on smoking.
With this model, the plutonium and external dose related ERRs are expressed relative to workers with the same smoking status.
With this model, the plutonium and external dose related ERRs are expressed relative to nonsmokers.
Set equal to zero since the estimate was negative; the estimated ERR per Gy was −0.26 (95% CI: <−0.26–1.30).