Etiology |
Cocaine inhibits the reuptake of norepinephrine at presynaptic terminals
Cocaine has a vasoconstrictive effect on arterial endothelium via changes in calcium channels
|
Incidence |
1.6% of U.S. adult population uses cocaine
Unknown incidence of cocaine enteropathy
|
Gender Ratio |
1.6:1 (Male:Female) for cocaine; approximately 1.1:1 (Male:Female) in sample of case reports for cocaine induced mesenteric ischemia[2] |
Age Predilection |
Affects all age groups, Average age 32 |
Risk Factors |
Cocaine use |
Treatment |
Cocaine cessation, supportive care |
Prognosis |
Can result in resolution of symptoms without permanent morbidity, but can also result in bowel infarction, hemorrhage, perforation, and death. |
Findings on Imaging |
Bowel wall thickening, changes in bowel wall attenuation, dilation of the bowel lumen, congestion of the mesenteric vessels, mesenteric free fluid, mesenteric fat stranding |