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. 2013 Feb 1;7(2):38–43. doi: 10.3941/jrcr.v7i2.1240

Table 1.

Summary table of cocaine-induced enteropathy

Etiology
  1. Cocaine inhibits the reuptake of norepinephrine at presynaptic terminals

  2. Cocaine has a vasoconstrictive effect on arterial endothelium via changes in calcium channels

Incidence
  1. 1.6% of U.S. adult population uses cocaine

  2. Unknown incidence of cocaine enteropathy

Gender Ratio 1.6:1 (Male:Female) for cocaine; approximately 1.1:1 (Male:Female) in sample of case reports for cocaine induced mesenteric ischemia[2]
Age Predilection Affects all age groups, Average age 32
Risk Factors Cocaine use
Treatment Cocaine cessation, supportive care
Prognosis Can result in resolution of symptoms without permanent morbidity, but can also result in bowel infarction, hemorrhage, perforation, and death.
Findings on Imaging Bowel wall thickening, changes in bowel wall attenuation, dilation of the bowel lumen, congestion of the mesenteric vessels, mesenteric free fluid, mesenteric fat stranding