Table 3.
Kidney function parameters before (Pre) and after 12 weeks (Post) of either creatine or placebo supplementation in resistance-trained individuals consuming a high-protein diet
| |
Creatine (n = 12) |
Placebo (n = 14) |
|
||
|---|---|---|---|---|---|
| Variable | Pre | Post | Pre | Post | P (group x time interaction) |
| Albuminuria (mg/24 h) |
19 (38) |
15 (28) |
8 (7) |
4 (2) |
0.99 |
| Proteinuria (g/24 h) |
0.14 (0.11) |
0.14 (0.10) |
0.10 (0.05) |
0.10 (0.07) |
0.83 |
| Urinary potassium (mEq/24 h) |
65 (24) |
59 (22) |
68 (24) |
65 (19) |
0.86 |
| Urinary sodium (mEq/24 h) |
231 (56) |
226 (91) |
195 (65) |
191 (52) |
0.99 |
| Serum potassium (mEq/L) |
4 (0.3) |
4 (0.4) |
5 (0.4) |
4 (0.4) |
0.26 |
| Serum sodium (mEq/L) |
141 (3) |
141 (2) |
142 (3) |
141 (4) |
0.53 |
| Serum creatinine (mg/dL) |
1.1 (0.1) |
1.2 (0.2) |
1.0 (0.1) |
1.1 (0.1) |
0.30 |
| Serum urea (mg/dL) | 41.7 (10.7) | 39.2 (11.7) | 33.3 (6.7) | 33.4 (7.2) | 0.63 |
Data expressed as mean (standard deviation). There were no significant differences between groups at baseline. No significant within- or between-group differences were noted. Note: Conversion factors for units: serum creatinine in mg/dL to mol/L, ×88.4; serum urea in mg/dL to mmol/L, ×0.166; glomerular filtration rate in mL/min/1.73 m2 to mL/s/1.73 m2, ×0.01667.