Table 3.

Antidiarrhoeal activity of methanolic extract and fractions against castor oil-induced diarrhoea in rats

Group	Dose (p.o.)	No. of faeces in 4 h	% inhibition of diarrhoea
Control	10 mL/kg, p.o.	22.5 ± 2.4	-
Loperamide	5 mg/kg, p.o.	9.5 ± 0.64*	57.78
Methanol	200 mg/kg, p.o.	15 ± 1.1*	33.33
	400 mg/kg, p.o.	11.5 ± 0.09*	48.89
Ethyl acetate	200 mg/kg, p.o.	16.25 ± 1.38*	27.78
	400 mg/kg, p.o.	11 ± 1.58*	51.11
Chloroform	200 mg/kg, p.o.	12 ± 1.29*	46.67
	400 mg/kg, p.o.	11.25 ± 1.25*	50
Pet. ether	200 mg/kg, p.o.	15.5 ± 1.76*	31.11
	400 mg/kg, p.o.	13.75 ± 1.38*	38.89

All values are expressed as mean ± SEM (n = 5); One-way analysis of variance (ANOVA) followed by Dunnett’s test. *P < 0.05, significant compared with the control samples.