Table 4.
Association between tSNP genotypes and the risk of glioma
| SNP ID | Genotype |
No. (frequency) |
Logistic regression |
||
|---|---|---|---|---|---|
| Case | Control | OR (95% CI) | P value | ||
| rs12022378 |
CC |
114(18.2) |
87(13.6) |
0.71(0.51-0.99) |
0.0418 |
| rs12022378 |
CT |
265(42.2) |
288(44.9) |
1.01(0.8-1.29) |
0.9127 |
| rs12022378 |
TT |
249(39.6) |
267(41.6) |
1(referent) |
|
| rs12917 |
TT |
6(1) |
10(1.6) |
1.7(0.61-4.72) |
0.3011 |
| rs12917 |
TC |
91(14.5) |
115(17.9) |
1.29(0.96-1.74) |
0.0956 |
| rs12917 |
CC |
530(84.5) |
519(80.6) |
1(referent) |
|
| rs12645561 |
TT |
43(6.8) |
56(8.7) |
1.26(0.83-1.93) |
0.2784 |
| rs12645561 |
TC |
251(40) |
241(37.6) |
0.93(0.74-1.18) |
0.5537 |
| rs12645561 |
CC |
334(53.2) |
344(53.7) |
1(referent) |
|
| rs7003908 |
CC |
31(4.9) |
43(6.7) |
1.44(0.89-2.33) |
0.1387 |
| rs7003908 |
CA |
201(32) |
217(33.7) |
1.12(0.88-1.42) |
0.3536 |
| rs7003908 |
AA |
397(63.1) |
383(59.6) |
1(referent) |
|
| rs6010620 |
GG |
75(11.9) |
40(6.2) |
0.46(0.31-0.7) |
0.0002 |
| rs6010620 |
GA |
261(41.5) |
267(41.5) |
0.89(0.71-1.12) |
0.3212 |
| rs6010620 |
AA |
293(46.6) |
337(52.3) |
1(referent) |
|
| rs2297440 |
CC |
73(11.6) |
40(6.2) |
0.47(0.31-0.71) |
0.0003 |
| rs2297440 |
CT |
263(41.8) |
263(40.8) |
0.86(0.68-1.08) |
0.1902 |
| rs2297440 |
TT |
293(46.6) |
342(53) |
1(referent) |
|
| rs4809324 |
CC |
11(1.8) |
7(1.1) |
0.62(0.24-1.6) |
0.3162 |
| rs4809324 |
CT |
129(20.5) |
133(20.7) |
1(0.76-1.31) |
0.9901 |
| rs4809324 |
TT |
488(77.7) |
504(78.3) |
1(referent) |
|
| rs2992 |
AA |
126(20.1) |
117(18.2) |
0.98(0.71-1.35) |
0.9003 |
| rs2992 |
AG |
292(46.5) |
328(50.9) |
1.19(0.92-1.52) |
0.1822 |
| rs2992 |
GG |
210(33.4) |
199(30.9) |
1(referent) |
|
| rs3770502 |
AA |
12(1.9) |
15(2.3) |
1.18(0.54-2.54) |
0.6809 |
| rs3770502 |
AG |
177(28.1) |
161(25) |
0.86(0.67-1.1) |
0.2198 |
| rs3770502 |
GG |
440(70) |
468(72.7) |
1(referent) |
|
| rs9288516 |
AA |
128(20.4) |
153(23.8) |
1.28(0.93-1.74) |
0.1249 |
| rs9288516 |
AT |
308(49.1) |
312(48.4) |
1.08(0.84-1.4) |
0.5539 |
| rs9288516 | TT | 191(30.5) | 179(27.8) | 1(referent) | |
OR odd ratio, CI confidence interval.