Table 7.
Associations between different clinicopatholiogical features and genotype frequency of GG in rs6010620, and CC in rs2297440 of RTEL1 gene in glioma patients (n = 75, 73, respectively)
|
Clinicopatholiogical features |
GG frequency |
P value |
CC frequency |
P value |
|---|---|---|---|---|
| n (%) | n (%) | |||
|
WHO grade |
|
|||
| I |
12 (16.0) |
>0.05 |
11 (14.7) |
>0.05 |
| II |
35 (46.7) |
|
35 (56.2) |
|
| III |
12 (16.0) |
|
13 (17.8) |
|
| IV |
16 (21.3) |
|
14 (19.2) |
|
|
Age |
|
|||
| ≥40 |
36 (48.0) |
NS |
40 (54.8) |
NS |
| <40 |
39 (52.0) |
|
33 (45.2) |
|
|
Gender |
|
|||
| Male |
30 (40.0) |
NS |
31 (42.5) |
NS |
| Female |
45 (60.0) |
|
42 (57.5) |
|
|
KPS |
|
|||
| ≥70 |
72 (96.0) |
>0.05 |
70 (95.9) |
>0.05 |
| <70 | 3 (4.0) | 3 (4.1) | ||
NS not significant, KPS Karnofsky performance score.