Table 1.
Patient characteristics according to CRT
| R5 | X4 | p value | |
|---|---|---|---|
| N patients |
68 (58%) |
50 (42%) |
|
| Male gender (N,%) |
52 (76%) |
36 (72%) |
0.6 |
| Age (years, mean ± SD) |
51.2 ± 5.6 |
50.6 ± 5.9 |
0.1 |
| Foreign nationality (N,%) |
1 (1.5%) |
1 (2.0%) |
0.8 |
| HIV-1 non B subtype (N,%) |
15 (22%) |
7 (14%) |
0.3 |
| Risk factor (N,%) |
|
|
|
| - parenteral |
44 (65%) |
27 (54%) |
|
| - sexual |
23 (34%) |
21 (42%) |
0.4 |
| ART duration (years; median, IQR) |
13 (9–16) |
14 (10–16) |
0.5 |
| - NRTIs |
13 (9–16) |
14 (10–16) |
0.6 |
| - NNRTIs |
4 (1–7) |
4 (2–6) |
1.0 |
| - PIs |
7 (5–9) |
6 (5–12) |
0.5 |
| Past use of mono- or bi-therapy (N,%) |
43 (63%) |
35 (70%) |
0.8 |
| Previous AIDS events (N,%) |
7 (10%) |
10 (20%) |
0.2 |
| Serious non-AIDS events (N,%) |
19 (39%) |
7 (14%) |
0.07 |
| HBsAg pos (N,%) |
9 (13%) |
4 (8%) |
0.1 |
| Anti-HCV pos (N,%) |
51 (75%) |
30 (60%) |
0.1 |
| pVL (log10 cp/ml;median, IQR) |
3.2 (3.2-4.8) |
4.1 (3.2-8.9) |
0.1 |
| Aviremic pts (N,%) |
53 (78%) |
36 (72%) |
|
| CD4+ cell count (median, IQR) |
|
|
|
| - absolute (n/mmc) |
658 (219–185) |
558 (109–1219) |
0.1 |
| - percentage (%) |
31 (24–53) |
28 (11–52) |
0.1 |
| Nadir CD4+ cell count |
|
|
|
| - absolute (median n/mmc;, IQR) |
137 (90–616) |
87 (27–382) |
0.005 |
| - percentage (%) | 11 (7–27) | 8 (2–32) | 0.01 |
Legend: N = number, SD = standard deviation; IQR = InterQuartile Range; pVL: HIV-1 plasma viral load.