Table 3.
Adverse Events of toremifene 120 mg and exemestane 25 mg in 88 treated patients
|
TOR120 (n = 43) |
EXE (n = 45) |
|||
|---|---|---|---|---|
| Grade1,2 | Grade3,4 | Grade1,2 | Grade3,4 | |
| Nausea |
4* |
0 |
1 |
0 |
| Fatigue |
3* |
0 |
1 |
0 |
| Hot flush |
3* |
- |
1 |
- |
| Night sweating |
3* |
- |
0 |
- |
| Vaginal bleeding, discharge |
2 |
- |
0 |
- |
| Joint pain, disorder |
1 |
- |
2 |
- |
| Liver dysfunction |
1 |
0 |
1 |
0 |
| Exanthema | 1 | 0 | 0 | 0 |
* Three of 43 women treated with toremifene 120 mg were withdrawn from the trial in a few days because of early nausea, fatigue, hot flush and night sweating, which were appeared in same 3 patients.