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. 2013 Apr 15;5:5. doi: 10.1186/2040-7378-5-5

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Copyright © 2013 Bueche et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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STL- (white), Glutathione- (red) and GFAP- (green) immunohistochemistry in a treated SHRSP. Glutathione is produced by astrocytes juxtapositioned to the small vessels’ endothelial cells (A &C). Comparing both groups, the treated one exhibited significant more Glutathione-positive vessels surrounded by astrocytes (D, histogram, y-axis with mean ratio of Glutathione-positive vessels in %). B – Negative control for Glutathione (Cy3 donkey x mouse) and GFAP (Cy5 donkey x chicken). DAPI - 4',6-diamidino-2-phenylindole, fluorescent stain for DNA detection. A, C hippocampal arteriole of a 26 weeks old SHRSP, magnification 630, ** p ≤ 0.05.