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. 2013 May 22;8(5):e64297. doi: 10.1371/journal.pone.0064297

Table 2. eat-4 mutants recorded with NeuroChip or conventional microelectrode recordings have the same phenotype.

Conventional recording NeuroChip
Eat-4(n2474) (n = 5)
EPG frequency (s−1) 0.055±0.007 0.090±0.015
EPG duration (s) 0.287±0.014****1 0.172±0.009****3
Average number of P waves 0.280±0.065*2 0.103±0.022****4
‘e’ amplitude (mV) 0.368±0.030 0.376±0.034
R-E interval (s) 26.513±3.078 22.288±3.867
R-E ratio 2.170±0.117 1.491±0.085

Data are the mean ± s.e.mean of recordings from ‘n’ worms. Each parameter was derived from AutoEPG analysis of all the EPGs captured in a recording of 5 minutes or, for manual analysis, from 60 EPGs. Eat-4 had increased pump duration and decreased number of ‘P’ waves compared to wild-type. Comparisons made by unpaired Student’s t-test to the respective parameters for 1,2 conventional wild-type N2 recording without 5-HT, P<0.0001 and P = 0.0208, respectively; or 3,4 to wild-type N2 NeuroChip recording without 5-HT, P<0.0001. Wild-type data are provided in Table 1.