Table 2. Analysis of the complement determining regions (CDR) of the different isotypes.

Isotype	Length of the variable region	Length of the CDR1H	Length of the CDR2H	Length of the CDR3H
IgM	131.65±14.62	8±0	7±0	25.65±14.62
IgD	138.70±17.54	8±0	7±0	32.70±17.54
IgG1-3	138.70±19.39	8±0	7±0	32.70±19.39
IgE	136.55±17.97	8±0	7±0	30.55±17.97
IgA	127.05±12.17	8±0	7±0	21.05±12.17

The average amino acid residue lengths of the complete variable region and the CDR regions, according to the IMGT nomenclature [39], are provided with their standard deviations. The size of the variable regions ranged from 111 to 173 amino acid residues. In total, 20 sequences per isotype were analyzed.