Table 4. Multivariate Cox regression analysis for vitamin D and other selected possible predictors of mortality in patients with AKI.

	25(OH)Dnmol/L		1, 25(OH)2Dpmol/L		BsmI		FokI		Age		Gender		SOFA score
	HR	p	HR	p	HR	p	HR	p	HR	p	HR	p	HR	p
Model 1	1.007	0.522	1.003	0.326	/	/	/	/	/	/	/	/	/	/
Model 2	1.006	0.571	1.003	0.404	0.409	0.224	1.172	0.739	/	/	/	/	/	/
Model 3	1.013	0.799	1.002	0.514	0.360	0.168	1.131	0.799	0.987	0.172	1.148	0.737	/	/
Model 4	1.007	0.593	1.004	0.136	0.759	0.721	0.639	0.360	0.998	0.843	0.571	0.220	1.314	<0.001

Note: The multivariate analysis sequentially adjusted the models for covariates as follows: Model 1, unadjusted; Model 2, adjusted for VDR polymorphisms; Model 3, adjusted for age, gender, and VDR polymorphisms; Model 4, adjusted for age, gender, SOFA score, and VDR polymorphisms.

Abbreviations: 25(OH)D, 25-hydroxyvitamin D; 1,25(OH)₂D, 1,25-dihydroxyvitamin D; SOFA, Sequential Organ Failure Assessment.