Table 1. Th1 and Th17 differentiation cytokines after 72 hours of stimulation.
Cytokine | Unstimulated TEC | Stimulated TEC |
IL-1β | N.D. | N.D. |
IL-6 | + | +++ |
IL-12p70 | N.D. | N.D. |
IL-17 | N.D. | N.D. |
IL-23 | N.D. | N.D. |
TGF-β1 | N.D. | N.D. |
N.D. not detectable; + cytokine present +++ significant upregulation; Stimulated TEC using combination of IFN-γ (50 ng/ml) and TNF-α (20 ng/ml).