Table 2. Correlation of ESCC Clinicopathological Features with Maspin Expression and Subcellular Localization.
Variable | Cases (n = 84) | Maspin Expression | P Value | Nuclear Maspin | P Value | Cytoplasmic Maspin | P Value | |||
Weak | Strong | Weak | Strong | Weak | Strong | |||||
Sex | ||||||||||
Male | 64 | 26 (40%) | 38 (60%) | 0.653 | 28 (43%) | 36 (57%) | 0.767 | 36(57%) | 28 (43) | 0.922 |
Female | 20 | 7 (35%) | 13 (65%) | 8 (40%) | 12 (60%) | 11 (55%) | 9 (45%) | |||
Age | ||||||||||
<60 | 42 | 16 (37%) | 26 (63%) | 0.823 | 17 (40%) | 25 (60%) | 0.659 | 25 (60%) | 17 (40%) | 0.510 |
≥60 | 42 | 17 (40%) | 25 (60%) | 19 (45%) | 23 (55%) | 22 (52%) | 20 (48%) | |||
Differentiation | ||||||||||
Well | 19 | 8 (43%) | 11 (57%) | 0.706 | 9 (47%) | 10 (53%) | 0.475 | 8 (41%) | 11 (69%) | 0.383 |
Moderate | 43 | 18 (42%) | 25 (58%) | 20 (46%) | 23 (54%) | 26 (60%) | 17 (40%) | |||
Poor | 22 | 7 (32%) | 15 (68%) | 7 (31%) | 15 (69%) | 13 (61%) | 9 (39%) | |||
Lymph node metastasis | ||||||||||
Negative | 33 | 11 (33%) | 22 (67%) | 0.369 | 14 (43%) | 19 (57%) | 0.949 | 18 (58%) | 15 (42%) | 0.834 |
Positive | 51 | 22 (43%) | 29 (56%) | 22 (40%) | 29 (60%) | 29 (60%) | 22 (40%) | |||
Pathologic stage | ||||||||||
I+II | 40 | 13 (32%) | 27 (65%) | 0.225 | 16 (40%) | 24 (60%) | 0.614 | 19 (48%) | 21 (52%) | 0.137 |
III | 44 | 20 (45%) | 24 (54%) | 20 (45%) | 24 (55%) | 28 (63%) | 16 (37%) |