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. 2013 May 22;8(5):e63581. doi: 10.1371/journal.pone.0063581

Table 2. Correlation of ESCC Clinicopathological Features with Maspin Expression and Subcellular Localization.

Variable Cases (n = 84) Maspin Expression P Value Nuclear Maspin P Value Cytoplasmic Maspin P Value
Weak Strong Weak Strong Weak Strong
Sex
Male 64 26 (40%) 38 (60%) 0.653 28 (43%) 36 (57%) 0.767 36(57%) 28 (43) 0.922
Female 20 7 (35%) 13 (65%) 8 (40%) 12 (60%) 11 (55%) 9 (45%)
Age
<60 42 16 (37%) 26 (63%) 0.823 17 (40%) 25 (60%) 0.659 25 (60%) 17 (40%) 0.510
≥60 42 17 (40%) 25 (60%) 19 (45%) 23 (55%) 22 (52%) 20 (48%)
Differentiation
Well 19 8 (43%) 11 (57%) 0.706 9 (47%) 10 (53%) 0.475 8 (41%) 11 (69%) 0.383
Moderate 43 18 (42%) 25 (58%) 20 (46%) 23 (54%) 26 (60%) 17 (40%)
Poor 22 7 (32%) 15 (68%) 7 (31%) 15 (69%) 13 (61%) 9 (39%)
Lymph node metastasis
Negative 33 11 (33%) 22 (67%) 0.369 14 (43%) 19 (57%) 0.949 18 (58%) 15 (42%) 0.834
Positive 51 22 (43%) 29 (56%) 22 (40%) 29 (60%) 29 (60%) 22 (40%)
Pathologic stage
I+II 40 13 (32%) 27 (65%) 0.225 16 (40%) 24 (60%) 0.614 19 (48%) 21 (52%) 0.137
III 44 20 (45%) 24 (54%) 20 (45%) 24 (55%) 28 (63%) 16 (37%)