Table 2. List of proteins showing significant differences between different groups (P-values <0.05) and their respective AUC values.

SerialNo.	Gene Symbol	Protein Name	Peptide Sequence	Area Under ROC curve
				Healthy control groupvs. Before HCC treatmentgroup	Before HCC treatment group vs. After HCC treatment group
1	ACADVL	Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	ASNTAEVFFDGVR	0.701	0.691
2	AFP	Alpha-fetoprotein	GYQELLEK	0.756	0.735
3	ANLN	Actin-binding protein anillin	TQSLPVTEK	0.920	0.744
4	BASP1	Brain acid soluble protein 1	AEGAATEEEGTPK	0.951	0.719
5	C4A	Complement C4-A	VGDTLNLNLR	0.867	0.710
6	CAPN1	Calpain-1 catalytic subunit	YLGQDYEQLR	0.946	0.586
7	FLNB	Filamin-B	APLNVQFNSPLPGDAVK	0.660	0.707
8	MTHFD1	C-1-tetrahydrofolatesynthase, cytoplasmic	GVPTGFILPIR	0.829	0.685
9	PABPC1	Polyadenylate-binding protein 1	EFSPFGTITSAK	0.949	0.608