Table 3. Pooled estimates (95% confidence limits) for sensitivity, specificity, likelihood ratio positive, likelihood ratio negative for 1) at least 1 CNS disease sign or symptom and 2) headache alone as predictors of meningitis.

	At least 1 sign/symptom	Headache alone
Sensitivity	1.00 [0.77, 1.00]	1.00 [0.77, 1.00]
Specificity	0.25 [0.13, 0.40]	0.59 [0.43, 0.74]
Likelihood Ratio Positive	1.25 [0.99, 1.59]	2.30 [1.55, 3.42]
Likelihood Ratio Negative	0.33 [0.07, 1.59]	0.15 [0.03, 0.68]