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Putative connection between protein thiol repair and autophagy. Lysosomal hydrolases degrade proteins into peptides (short lines) and amino acids (dots), which are transported out of the autophagolysosome, where they may enter the gamma-glutamyl cycle to generate glutathione, which is utilized by thiol repair enzymes associated with the autophagolysosome, including glutathione S-transferase, aryl sulfotransferase and betaine:homocysteine S-methyltransferase
