Table 2.
Measures of Fat distribution Among Metabolically Healthy and Metabolically Abnormal Hispanics in the IRAS Family Study.*
Obese Phenotype | Overweight Phenotype | Normal Weight** (n=234) |
|||||||
---|---|---|---|---|---|---|---|---|---|
Metabolically healthy (n=74) |
Metabolically abnormal (n=323) |
1P-value | Metabolically healthy (n=138) |
Metabolically abnormal (n=201) |
2P-value | 3P-value | 4P-value | ||
VAT, cm2 | 107.7 (5.9) | 127.7 (4.7) | 0.0005 | 106.3 (3.1) | 117.1 (3.1) | 0.0083 | 103.3 (4.7) | 0.6078 | 0.4160 |
SAT∫, cm2 | 458.9 (13.4) | 476.0 (7.0) | 0.2546 | 293.7 (6.7) | 302.3 (5.4) | 0.3186 | 171.8 (4.7) | <0.0001 | <0.0001 |
VSR | 0.33 (0.02) | 0.37 (0.02) | 0.0205 | 0.35 (0.01) | 0.39 (0.01) | 0.0044 | 0.37 (0.02) | 0.0830 | 0.0843 |
Liver Density+ (HU) | 51.1 (1.7) | 44.9 (1.4) | 0.0002 | 53.6 (1.3) | 51.5 (1.2) | 0.1642 | 57.5 (1.4) | 0.0132 | 0.0145 |
LSR + | 1.10 (0.03) | 0.98 (0.03) | 0.0008 | 1.17 (0.03) | 1.10 (0.02) | 0.0383 | 1.24 (0.03) | 0.0087 | 0.0534 |
% Fat from DXA+ | 33.3 (0.7) | 33.6 (0.4) | 0.6445 | 32.7 (0.5) | 32.9 (0.4) | 0.6988 | 30.6 (0.6) | 0.0057 | 0.0008 |
% Lean from DXA+ | 64.1 (0.7) | 63.8 (0.3) | 0.6898 | 64.5 (0.5) | 64.3 (0.3) | 0.7097 | 66.4 (0.5) | 0.0104 | 0.0016 |
Adjusted for age, gender, and clinic, liver enzymes, and BMI (Adjusted mean (SE) values with p-values indicating obese and overweight group differences; p <0.05 indicates significant differences between MH and MA groups).
Normal Weight metabolically healthy (MH) participants only.
Measures obtained at follow-up, sample sizes reduced by approximately 20%
SAT not adjusted for BMI
p-values comparing metabolically healthy obese to metabolically abnormal obese
p-values comparing metabolically healthy overweight to metabolically abnormal overweight
p-values comparing normal weight to metabolically healthy obese
p-values comparing normal weight to metabolically healthy overweight