Table 3.
Multivariate-adjusted odds ratio (95% CI) for metabolic syndrome by leg fat indices, by ethnicity.
| Non-Hispanic White | Non-Hispanic Black | Hispanic groups | Totalf | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Q1 | Q3 | Q5 | Q1 | Q3 | Q5 | Q1 | Q3 | Q5 | Q1 | Q3 | Q5 | ||
| Leg FM, kg | Leg FM, kg | ||||||||||||
| MetS/Controla | 59/343 | 107/296 | 166/237 | 7/138 | 26/119 | 46/99 | 47/187 | 78/156 | 101/133 | MetS/Controla | 113/668 | 211/571 | 313/469 |
| Multivariate-adjustedb | 1.0 | 0.64 (0.50, 0.81) | 0.41 (0.24, 0.71) | 1.0 | 1.91 (0.65, 5.63) | 0.70 (0.20, 2.44) | 1.0 | 0.53 (0.32, 0.89) | 0.32 (0.19, 0.53) | Model 1d | 1.0 | 0.62 (0.40, 0.96) | 0.38 (0.22, 0.68) |
| Leg FM% | Leg FM% | ||||||||||||
| MetS/Controla | 67/335 | 131/272 | 134/269 | 7/138 | 40/105 | 41/104 | 50/184 | 99/135 | 96/138 | MetS/Controla | 124/657 | 270/512 | 271/511 |
| Multivariate-adjustedb | 1.0 | 0.40 (0.27, 0.62) | 0.27c (0.18, 0.41)d | 1.0 | 0.53 (0.10, 2.81) | 0.06 (0.01, 0.42)d | 1.0 | 0.50 (0.27, 0.90) | 0.18c (0.08, 0.38)d | Model 1b | 1.0 | 0.42 (0.26, 0.67) | 0.22c (0.11, 0.44)d |
| Leg/Whole | Leg/Whole | ||||||||||||
| MetS/Controla | 212/190 | 104/299 | 27/376 | 57/88 | 29/116 | 11/134 | 132/102 | 78/156 | 28/206 | MetS/Controla | 401/380 | 211/571 | 66/716 |
| Multivariate-adjustedb | 1.0 | 0.28 (0.22, 0.36) | 0.04c (0.02, 0.06)d | 1.0 | 0.33 (0.21, 0.51) | 0.06c (0.03, 0.11)d | 1.0 | 0.30 (0.22, 0.42) | 0.08c (0.04, 0.17)d | Model 1b | 1.0 | 0.29 (0.20, 0.41) | 0.05c (0.03, 0.08)d |
| Leg/Trunk | Leg/Trunk | ||||||||||||
| MetS/Controla | 215/187 | 103/300 | 24/379 | 62/83 | 23/122 | 7/138 | 138/96 | 79/155 | 25/209 | MetS/Controla | 415/366 | 205/577 | 56/726 |
| Multivariate-adjustedb | 1.0 | 0.25 (0.22, 0.28) | 0.03c (0.02, 0.04)d | 1.0 | 0.19 (0.12, 0.33) | 0.04c (0.01, 0.10)d | 1.0 | 0.26 (0.18, 0.39) | 0.07c (0.02, 0.24)d | Model 1b | 1.0 | 0.24 (0.17, 0.35) | 0.04c (0.02, 0.06)d |
Abbreviations: FM, fat mass; FM%, fat mass percent; MetS, metabolic syndrome.
Number of metabolic syndrome cases and controls were calculated based on the first imputation dataset. We only included subjects who had non-missing MetS components in this analysis.
Adjusted for age (yrs), gender (men, women), education (high school or below, any college, and college graduate or above), regular moderate-to-vigorous physical activity (yes, no), smoking status (nonsmoker, past smoker, or current smoker), alcohol consumption (nondrinker, 1-3 drinks/day, or ≥4 drinks/day), self-reported cardiovascular disease (yes, no), and family history of diabetes or cardiovascular disease (yes, no), as well as trunk FM when modeling association for leg FM or trunk FM% when modeling association for leg FM%. Ethnicity was further adjusted for when examining these correlations in total population.
Significant Bonferroni-corrected P value for odds ratios comparing extreme quintiles (P < 0.00028).
Significant Bonferroni-corrected P value for linear trend (P < 0.00028).
Included non-Hispanic white, non-Hispanic black, and Hispanic groups.