Table 3b.
Univariate probabilities of outcomes by whether received prior autologous transplant
| Did not receive prior auto | Received prior auto | P-value | |||
|---|---|---|---|---|---|
|
| |||||
| Outcome event | N eval. | Prob (95% CI)a | N eval. | Prob (95% CI)a | |
| ANC > 0.5 × 109/L | 69 | 42 | |||
| @ 28 days | 78 (66-86) | 90 (76-96) | 0.0806 | ||
| @100 days | 88 (78-94) | 98 (84-100) | 0.0433 | ||
| Platelets > 20 × 109 /L | 54 | 41 | |||
| @ 60 days | 65 (50-76) | 47 (28-64) | 0.1309 | ||
| @100 days | 69 (54-79) | 50 (30-67) | 0.1115 | ||
| Acute GVHD, Grades 2-4 | 65 | 38 | |||
| @100 days | 23 (14-34) | 37 (22-52) | 0.1466 | ||
| @ 180 days | 25 (15-36) | 37 (22-52) | 0.202 | ||
| Chronic GVHD | 68 | 44 | |||
| @ 1 year | 10 (5-19) | 19 (9-32) | 0.2359 | ||
| @ 3 years | 12 (6-21) | 19 (9-32) | 0.3395 | ||
| @5 years | 12 (6-21) | 19 (9-32) | 0.3395 | ||
| Transplant-related mortality | 73 | 42 | |||
| @ 100days | 19 (11-29) | 17 (7-29) | 0.7332 | ||
| @ 1 year | 25 (16-35) | 24 (12-37) | 0.8916 | ||
| @ 3 years | 26 (17-37) | 24 (12-37) | 0.7572 | ||
| @ 5 years | 26 (17-37) | 24 (12-37) | 0.7572 | ||
| Relapse | 73 | 42 | |||
| @ 1 year | 27 (17-38) | 57 (41-70) | 0.0012 | ||
| @ 3 years | 43 (31-55) | 67 (50-79) | 0.0131 | ||
| @ 5 years | 46 (34-58) | 70 (53-82) | 0.0123 | ||
| Disease-free survival | 73 | 42 | |||
| @ 1 year | 48 (36-59) | 19 (9-32) | 0.0006 | ||
| @ 3 years | 30 (20-41) | 10 (3-21) | 0.0037 | ||
| @ 5 years | 27 (17-38) | 6 (1-17) | 0.0018 | ||
| Overall survival | 97 | 46 | |||
| @ 1 year | 59 (48-68) | 50 (35-64) | 0.3439 | ||
| @ 3 years | 36 (26-46) | 16 (7-28) | 0.0086 | ||
| @ 5 years | 29 (20-39) | 7 (1-18) | 0.0005 | ||