Table 3c.
Univariate probabilities of outcomes by donor type
| HLA-identical sibling | Other related | Unrelated | P-value | ||||
|---|---|---|---|---|---|---|---|
|
| |||||||
| Outcome event | N eval. |
Prob (95% CI)a | N eval. |
Prob (95% CI)a | N eval. |
Prob (95% CI)a | |
| ANC > 0.5 × 109/L | 50 | 23 | 38 | ||||
| @ 28 days | 86 (72-93) | 87 (64-96) | 76 (59-87) | 0.4703 | |||
| @100 days | 92 (80-97) | 87 (64-96) | 95 (81-99) | 0.6149 | |||
| Platelets > 20 × 109 /L | 39 | 19 | 37 | ||||
| @ 60 days | 65 (48-78) | 63 (38-80) | 45 (27-61) | 0.199 | |||
| @100 days | 68 (50-81) | 63 (38-80) | 51 (32-66) | 0.3311 | |||
| Acute GVHD, Grades 2-4 | 51 | 19 | 33 | ||||
| @100 days | 25 (15-38) | 21 (7-41) | 36 (20-52) | 0.4306 | |||
| @ 180 days | 25 (15-38) | 21 (7-41) | 40 (23-56) | 0.2802 | |||
| Chronic GVHD | 53 | 21 | 38 | ||||
| @ 1 year | 12 (5-22) | 19 (6-38) | 14 (5-27) | 0.7333 | |||
| @ 3 years | 12 (5-22) | 24 (9-43) | 14 (5-27) | 0.489 | |||
| @5 years | 12 (5-22) | 24 (9-43) | 14 (5-27) | 0.489 | |||
| Transplant-related mortality | 55 | 21 | 39 | ||||
| @ 100days | 18 (9-29) | 19 (6-38) | 18 (8-31) | 0.9944 | |||
| @ 1 year | 24 (14-36) | 34 (15-54) | 21 (10-34) | 0.5397 | |||
| @ 3 years | 26 (15-38) | 34 (15-54) | 21 (10-34) | 0.5397 | |||
| @ 5 years | 26 (15-38) | 34 (15-54) | 21 (10-34) | 0.5436 | |||
| Relapse | 55 | 21 | 39 | ||||
| @ 1 year | 30 (18-42) | 15 (4-33) | 63 (46-76) | <.0001 | |||
| @ 3 years | 52 (38-64) | 25 (9-45) | 66 (49-79) | 0.0043 | |||
| @ 5 years | 56 (41-68) | 31 (13-51) | 66 (49-79) | 0.0263 | |||
| Disease-free survival | 55 | 21 | 39 | ||||
| @ 1 year | 47 (33-59) | 51 (28-70) | 16 (7-29) | 0.0007 | |||
| @ 3 years | 22 (12-34) | 41 (20-61) | 13 (5-26) | 0.079 | |||
| @ 5 years | 19 (10-30) | 35 (15-55) | 13 (5-26) | 0.2133 | |||
| Overall survival | 74 | 29 | 40 | ||||
| @ 1 year | 63 (51-73) | 60 (39-75) | 40 (25-55) | 0.0529 | |||
| @ 3 years | 30 (19-41) | 48 (28-65) | 16 (7-29) | 0.0175 | |||
| @ 5 years | 22 (13-33) | 33 (16-52) | 16 (7-29) | 0.3101 | |||