Table 4.

(A) Release kinetics (% release per day) of TGF-γ3 (n=5) and (B) release kinetics (% release per day) of active TGF-γ3 (n=4) from OPF composite hydrogels in phase 1 (~ 24 hrs), phase 2 (1–4 days), phase 3 (4–8 days), and phase 4 (18–28 days).

(A)
Experimental Groups	Phase 1 (%/day) (~ 24 hrs)		Phase 2 (%/day) (Days 1 – 4)		Phase 3 (%/day) (Days 4 –18)		Phase 4 (%/day) (Days 18–28)
	Collagenase- PBS	PBS	Collagenase- PBS	PBS	Collagenase- PBS	PBS	Collagenase -PBS	PBS
Group 2, 1×	25.0 ± 3.1*	28.8 ± 3.3*	2.5 ± 0.4	1.7 ± 0.3	2.1 ± 0.3	2.1 ± 0.3	1.3 ± 0.7	1.2 ± 0.3
Group 3, 1×	17.1 ± 3.2	19.5 ± 1.0	6.5 ± 1.2*	1.7 ± 0.3	3.1 ± 0.1*	3.3 ± 0.4*	1.1 ± 0.2	0.9 ± 0.1

(B)
Experimental Groups	Phase 1 (%/day) (~ 24 hrs)	Phase 2 (%/day) (Days 1 – 4)	Phase 3 (%/day) (Days 4–18)	Phase 4 (%/day) (Days 18–28)
Group 2, 1×	25.6 ± 2.7	1.6 ± 0.6	1.0 ± 0.3	1.4 ± 0.6
Group 3,1×	24.4 ± 5.1	3.1 ± 0.6*	1.8 ± 0.1*	1.0 ± 0.1

^(*)indicates a significant difference between Group 2 (Gel loading) and Group 3 (GMP loading) in the same phase (p<0.05).