Table 2. List of 68 genes that displayed significant expression changes in the LS of lactating maternal mice compared to both virgin and pups removed groups.
| Accession No. | Gene Symbol | Gene Title | Fold Change (vs.pups removed) | Fold Change(vs. virgin) | |
| Cell cycle, adhesion, division, death, differentiation and proliferation | |||||
| NM_170597 | Creg2 | cellular repressor of E1A-stimulated genes 2 | 0.90 | 0.92 | |
| NM_001166273 | Cspg5 | chondroitin sulfate proteoglycan 5 | 0.90 | 0.92 | |
| NM_183187 | Fam107a | family with sequence similarity 107, member A | 1.26 | 1.17 | |
| NM_011812 | Fbln5 | fibulin 5 | 1.24 | 1.19 | |
| NM_010218 | Fjx1 | four jointed box 1 (Drosophila) | 0.84 | 0.87 | |
| NM_008538 | Marcks | myristoylated alanine rich protein kinase C substrate | 0.90 | 0.88 | |
| NR_033728 | Nit1 | nitrilase 1 | 1.06 | 1.08 | |
| NM_011386 | Skil | SKI-like | 0.87 | 0.83 | |
| Metabolic | |||||
| NM_001081204 | B3galtl | beta 1,3-galactosyltransferase-like | 0.91 | 0.92 | |
| NM_028979 | Cyp2j9 | cytochrome P450, family 2, subfamily j, polypeptide 9 | 1.18 | 1.14 | |
| NM_172948 | Mgat5b | mannoside acetylglucosaminyltransferase 5, isoenzyme B | 0.88 | 0.91 | |
| NM_172267 | Phyhd1 | phytanoyl-CoA dioxygenase domain containing 1 | 1.27 | 1.20 | |
| NM_029614 | Prss23 | protease, serine, 23 | 1.17 | 1.17 | |
| NM_001101430 | Psmg4 | proteasome (prosome, macropain) assembly chaperone 4 | 0.90 | 0.91 | |
| NM_133670 | Sult1a1 | sulfotransferase family 1A, phenol-preferring, member 1 | 1.34 | 1.30 | |
| Phosphorylation, dephosphorylation | |||||
| NM_009652 | Akt1 | thymoma viral proto-oncogene 1 | 0.93 | 0.92 | |
| NM_008587 | Mertk | c-mer proto-oncogene tyrosine kinase | 1.26 | 1.24 | |
| NM_016891 | Ppp2r1a | protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform | 0.95 | 0.95 | |
| Protein ubiquitination, deubiquitination | |||||
| NM_173784 | Ubtd2 | ubiquitin domain containing 2 | 0.87 | 0.90 | |
| NM_144873 | Uhrf2 | ubiquitin-like, containing PHD and RING finger domains 2 | 1.13 | 1.14 | |
| Regulation of transcription | |||||
| BC024814 | BC024814 | cDNA sequence BC024814 | 0.87 | 0.90 | |
| NM_023876 | Elp4 | elongation protein 4 homolog (S. cerevisiae) | 0.91 | 0.93 | |
| NM_133658 | Ercc3 | excision repair cross-complementing rodent repair deficiency, complementation group 3 | 0.93 | 0.93 | |
| NM_178213 | Hist2h2ab | histone cluster 2, H2ab | 0.89 | 0.87 | |
| NM_175662 | Hist2h2ac | histone cluster 2, H2ac | 0.90 | 0.88 | |
| NM_001033713 | Mef2a | myocyte enhancer factor 2A | 0.93 | 0.91 | |
| NR_030470 | Mir669a-2 | microRNA 669a-2 | 1.24 | 1.20 | |
| NM_181650 | Prdm4 | PR domain containing 4 | 0.93 | 0.95 | |
| NM_001166410 | Rbm3 | RNA binding motif protein 3 | 0.70 | 0.76 | |
| NM_001024918 | Rfx4 | regulatory factor X, 4 (influences HLA class II expression) | 0.86 | 0.89 | |
| NM_029949 | Snapc3 | small nuclear RNA activating complex, polypeptide 3 | 1.06 | 1.07 | |
| NM_001168578 | Tceal8 | transcription elongation factor A (SII)-like 8 | 0.88 | 0.86 | |
| NM_172913 | Tox3 | TOX high mobility group box family member 3 | 0.87 | 0.86 | |
| NM_001164578 | Tsr2 | TSR2, 20S rRNA accumulation, homolog (S. cerevisiae) | 0.94 | 0.91 | |
| NM_144546 | Zfp119a | zinc finger protein 119a | 0.87 | 0.89 | |
| Signal transduction | |||||
| NM_133237 | Apcdd1 | Adenomatosis polyposis coli down-regulated 1 | 0.83 | 0.88 | |
| NM_008533 | Cd180 | CD180 antigen | 0.86 | 0.84 | |
| NM_009895 | Cish | cytokine inducible SH2-containing protein | 1.20 | 1.20 | |
| NM_010108 | Efna3 | ephrin A3 | 0.91 | 0.89 | |
| NM_207655 | Egfr | epidermal growth factor receptor | 0.89 | 0.85 | |
| NM_053072 | Fgd6 | FYVE, RhoGEF and PH domain containing 6 | 1.09 | 1.08 | |
| NM_175668 | Gpr4 | G protein-coupled receptor 4 | 1.18 | 1.19 | |
| NM_001081298 | Lphn2 | latrophilin 2 | 0.89 | 0.86 | |
| NM_001083897 | Mpzl1 | myelin protein zero-like 1 | 0.91 | 0.91 | |
| NM_019515 | Nmu | neuromedin U | 1.35 | 1.42 | |
| NM_152229 | Nr2e1 | nuclear receptor subfamily 2, group E, member 1 | 0.87 | 0.85 | |
| NM_178751 | Orai2 | ORAI calcium release-activated calcium modulator 2 | 0.86 | 0.86 | |
| NM_027571 | P2ry12 | purinergic receptor P2Y, G-protein coupled 12 | 0.88 | 0.87 | |
| NM_001042499 | Rabl3 | RAB, member of RAS oncogene family-like 3 | 0.92 | 0.91 | |
| NM_007706 | Socs2 | suppressor of cytokine signaling 2 | 1.32 | 1.30 | |
| NM_133789 | Strn4 | striatin, calmodulin binding protein 4 | 0.93 | 0.92 | |
| Transport | |||||
| NM_027560 | Arrdc2 | arrestin domain containing 2 | 1.11 | 1.13 | |
| NM_010634 | Fabp5 | fatty acid binding protein 5, epidermal | 0.79 | 0.81 | |
| NM_021272 | Fabp7 | fatty acid binding protein 7, brain | 0.69 | 0.71 | |
| NM_175112 | Rae1 | RAE1 RNA export 1 homolog (S. pombe) | 0.94 | 0.92 | |
| NM_009155 | Sepp1 | selenoprotein P, plasma, 1 | 1.17 | 1.08 | |
| NM_178639 | Sfxn5 | sideroflexin 5 | 0.93 | 0.93 | |
| NM_146198 | Slc5a11 | solute carrier family 5 (sodium/glucose cotransporter), member 11 | 1.14 | 1.21 | |
| NM_138599 | Tomm70a | translocase of outer mitochondrial membrane 70 homolog A (yeast) | 0.90 | 0.88 | |
| Other | |||||
| NM_025675 | Atpbd4 | ATP binding domain 4 | 0.86 | 0.91 | |
| BC090976 | BC022687 | cDNA sequence BC022687 | 0.89 | 0.90 | |
| NM_001166164 | Ccdc74a | coiled-coil domain containing 74A | 0.89 | 0.89 | |
| NM_030179 | Clip4 | CAP-GLY domain containing linker protein family, member 4 | 0.91 | 0.88 | |
| NM_153507 | Cpne2 | copine II | 0.91 | 0.92 | |
| NM_146067 | Cpped1 | calcineurin-like phosphoesterase domain containing 1 | 0.86 | 0.88 | |
| NM_026062 | Fam69a | family with sequence similarity 69, member A | 0.87 | 0.87 | |
| NM_001033550 | Lrrc8b | leucine rich repeat containing 8 family, member B | 0.92 | 0.92 | |
| NM_026845 | Ppil1 | peptidylprolyl isomerase (cyclophilin)-like 1 | 0.87 | 0.83 | |
| NM_024196 | Tbc1d20 | TBC1 domain family, member 20 | 0.90 | 0.89 | |
The genes in Table 2 have FDR-adjusted p-values for each individual comparison under 0.25. Expression is given as fold change in lactating maternal LS relative to pups removed or virgin groups.