Table 1.
CKD risk factors and GFR by each method in the GENOA and ECAC cohort study samples
| Combined (N=1093) | GENOA (n=687) | ECAC (n=406) | |
|---|---|---|---|
| CKD risk factors | Mean ± SD or % | Mean ± SD or % | Mean ± SD or % |
|
| |||
| Age (at time of GFR measurements), y | 65 ± 9 | 65 ± 9 | 66 ± 9 |
| Sex (male) | 43% | 41% | 48% |
| Body mass index, kg/m2 | 30.2 ± 5.8 | 31.1 ± 5.9 | 28.8 ± 5.2 |
| 24-h urine albumin, mg | 21 ± 61 | 24 ± 61 | 16 ± 60 |
| 24-h urine creatinine, mg | 1311 ± 467 | 1293 ± 464 | 1342 ± 470 |
| Urine albumin to creatinine ratio | 16 ± 54 | 19 ± 58 | 12 ± 46 |
| Urine albumin to creatinine ratio ≥ 30 mg/g | 8.1% | 11% | 4.2% |
| Hypertension | 54% | 73% | 22% |
| Diabetes | 11% | 13% | 6.9% |
| Smoker | 7.4% | 7.3% | 7.5% |
| High-density lipoprotein cholesterol, mg/dl | 51 ± 16 | 51 ± 17 | 53 ± 16 |
| Log triglycerides, mg/dl | 4.7 ± 0.48 | 4.8 ± 0.48 | 4.6 ± 0.46 |
| Log C-reactive protein, mg/dl | 0.6 ± 1.0 | 0.7 ± 1.1 | 0.5 ± 1.0 |
| Uric acid, mg/dl | 5.6 ± 1.5 | 5.8 ± 1.5 | 5.3 ± 1.4 |
|
| |||
| GFR method | Mean ± SD or % | Mean ± SD or % | Mean ± SD or % |
|
| |||
| mGFR, ml/min/1.73 m2 | 80 ± 21 | 80 ± 21 | 79 ± 21 |
| eGFRCr, ml/min/1.73 m2 | 83 ± 15 | 83 ± 17 | 84 ± 13 |
| eGFRCysC, ml/min/1.73 m2 | 80 ± 20 | 78 ± 21 | 82 ± 19 |
| eGFRCr-CysC, ml/min/1.73 m2 | 82 ± 17 | 81 ± 19 | 84 ± 15 |
| Creatinine clearance, ml/min/1.73 m2 | 98 ± 29 | 97 ± 30 | 101 ± 26 |