Fig. 4.

Average predicted parameter (a–f) and R² (g) values for the constitutive model. Parameters were determined for individual WT and Eln+/− aortas via constrained nonlinear least squares regression and then averaged for each age and genotype. Parameters for each individual aorta are provided in Supplemental Table 1. For clarity, significant differences between ages are not shown, but are discussed in the text. The parameters c₁, c₂, and α are significantly affected by age (P < .001). * P < .05 between WT and Eln+/−. N = 5−10 for each age and genotype. Mean ± SD