Table 3.
Histopathologic features of non-diagnostic and diagnostic duodenal biopsies.
| Patient | Non-diagnostic EGD Original Histopathology |
Non-diagnostic EGD Histopathology Re-review |
Diagnostic EGD |
|---|---|---|---|
| A | Focal mild inflammation/normal villi | Normal | Marsh 3A |
| B | Focal IEL, normal villi | Marsh 3A | Marsh 3A |
| C | Unremarkable | Normal* | Marsh 3A |
| D | Within normal limits | Normal | Marsh 3A |
| E | Mildly chronically inflamed | Normal | Marsh 3A |
| F | Histologically unremarkable | Normal* | Marsh 3A |
| G | Mildly inflamed | Marsh 3A | Marsh 3A |
*
Villous tip clustering of intraepithelial lymphocytes was evident despite normal villous architecture and absence of significant lamina propria inflammation. This pattern has been described in individuals with latent celiac disease.