Table 4.
Number of patients with positive immunostaining and the immunohistochemical proportion scores (mean±SD) of each subtype of lung cancer
| Target | Adenocarcinoma | Squamous cell carcinoma | Small cell carcinoma | Non-neoplastic lung tissue*1 |
|---|---|---|---|---|
| CK5/6 | 5/33 (15.2%)0.31±0.69 | 11/11 (100%)*3.00±0.00 | 0/8 (0%)0.00 | 5/5 (100%)3.00±0.00 |
| CK7 | 30/33 (90.9%)*2.44±0.98 | 2/11 (18.2%)0.45±1.04 | 1/8 (12.5%)0.13±0.35 | 5/5 (100%)2.60±0.55 |
| CK14 | 2/31 (6.5%)0.17±0.46 | 11/11 (100%)*2.18±0.87 | 0/8 (0%)0.00 | 0/5 (0%)0.00 |
| CK18 | 27/27 (100%)*2.81±0.57 | 6/12 (50.0%)0.75±0.97 | 1/8 (12.5%)0.13±0.35 | 5/5 (100%)4.00±0.00 |
| CK19 | 26/32 (81.3%)1.57±1.09 | 6/12 (50.0%)1.17±1.27 | 0/8 (0%)0.00 | 5/5 (100%)0.55±1.40 |
| TTF-1 | 22/33 (66.7%)*1.74±0.46 | 1/12 (8.3%)0.08±0.29 | 4/8 (50.0%)1.28±1.25 | 0/5 (0%)0.00 |
*1: Non-neoplastic lung tissues were epithelium and tracheal gland.
*P<0.05, Mann-Whitney’s U test between adenocarcinoma and squamous cell carcinoma.
Proportion score determined by the ratio of positive staining cells: 0, none; 1, <10%; 2, 10–50%; 3, 51–80%; 4 >80%.